To create a mouse model of the human disease Hemophilia A, in which a nonfunctional factor VIII protein results in a blood clotting deficiency, _____
a. a cloned mutant FVIII gene is inserted into fertilized mouse eggs, which are then transferred to a foster mother for gestation and birth
b. a cloned normal FVIII gene is inserted into fertilized mouse eggs, which are then transferred to a foster mother for gestation and birth
c. mice with similar, naturally occurring, clotting deficiencies are cloned
d. embryonic stem cells are harvested from mouse blastocysts, and grown in the lab to produce blood cells for experimental research
e. adult mice are infected with bacteria that contain a copy of a mutant human FVIII gene
a
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What will be an ideal response?
________, the most common type of nonrandom mating, will not change allelic frequencies, but it will change genotypic frequencies toward homozygosity
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The science of comparative genomics to study human gene function is possible because much of the human genome is
conserved among other closely related species. Indicate whether the statement is true or false.
Embryonic stem cells cannot develop into ____ cells
a. muscle b. nerve c. blood d. placental e. other stem