Which of the following drugs may cause "Red man syndrome"?

A) penicillin
B) vancomycin
C) bupropion
D) cefaclor


B) vancomycin
Vancomycin may cause Red man syndrome, which is a rare condition involving degranulation of the mast cells that is independent of preformed complement or IgE. Other drugs that cause Red man syndrome include amphotericin B, ciprofloxacin, rifampicin, and teicoplanin. Usually, wheals and urticaria of the skin develop on the neck, arms, and upper trunk.

Health Professions

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