When the nurse is assessing a 2-day-old newborn and suspects Down syndrome, what factors would lead to this assessment? Select all that apply
A) Flat facial profile
B) Downward slant to the eyes
C) Large tongue compared to mouth
D) Simian crease
E) Epicanthal folds
F) Rigid joints
Ans: A, C, D, E
Common clinical manifestations of Down syndrome include flat facial profile, upward slant to the eyes (oblique palpebral fissures), tongue that is large in comparison to the mouth size, simian, crease, epicanthal folds, and loose joints.
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