The chemiosmotic model of ATP synthesis is based on each of the following lines of experimental evidence except
A) Artificial proton gradients established by addition of acid can drive ATP synthesis in the absence of electron transport.
B) Oxidative phosphorylation does not require a membrane-enclosed compartment.
C) Electron transport causes protons to be pumped out of the mitochondrial matrix.
D) The proton gradient established by electron transport has enough energy to drive ATP synthesis.
E) Uncoupling agents abolish both the proton gradient and ATP synthesis.
Answer: B
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