The same DNA probe used to measure mRNA levels by northern blotting can also be used on a Southern blot with a restriction digest of genomic DNA
What new information can be gained from Southern blotting (that wasn't already obtained by the northern blot analysis)? A) the level of protein that is being translated from the mRNA transcript
B) the presence of a unique restriction fragment pattern indicating a mutation in a known restriction site
C) the size of the genomic DNA fragments, including both introns and exons
D) the size of the genomic DNA fragments and the level of protein being translated
E) the size of the genomic DNA fragments and the presence of a unique restriction fragment pattern indicating a mutation in a known restriction site (both B and C)
E
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Which of the following statements about smooth muscle in arterioles is FALSE?
A) The muscle is multi-unit smooth muscle. B) Muscle contraction is under intrinsic controls. C) Muscle contraction is under extrinsic controls. D) The muscle forms rings around the arteriole. E) The muscle has inherent (myogenic) tone
Virginia was working as an undergraduate lab technician, and the graduate student she was working with instructed her to take some E. coli, and treat the culture with MgCl2 and CaCl2 to make the cells competent. Once Virginia produced the competent cells, she was able to
A. make them susceptible to bacteriophage B. make them pass their DNA to a recipient cell via conjugation C. make them take up naked DNA from their environment D. make them replicate their own DNA without an origin of replication E. None of the answers are correct.
CRISPR was first discovered in fungi, where it acts as a form of immune defense against invading bacteria.
Answer the following statement true (T) or false (F)
If a new anti-cancer drug is found effective in initial tests with mice, what do researchers conclude?
(a). If the drug was effective in a large number of mice, it will therefore be effective in humans. (b). If the drug was effective in a small proportion of mice, it will be effective in a small proportion of humans. (c). The mice have provided a positive control in this experiment that proves the drug is effective in humans. (d). The drug is effective in the mouse model; it must still be tested in humans. (e). The effect of the drug on mice has no bearing on the effect of the drug on humans.