Salicylates are very popular anti-inflammatory drugs because they:
1. are given primarily by the IM or IV route.
2. have no adverse effect on blood clotting.
3. have minimal-to-no side effects.
4. reduce pain.
Correct Answer: 4
Rationale 1: Salicylates are rarely given by the IM or IV route; most are provided orally.
Rationale 2: Salicylates inhibit platelet aggregation.
Rationale 3: In addition to GI bleeding, aspirin can cause dyspepsia, nausea, and ulcer perforation. When taken for long periods of time, salicylism (toxicity) could occur.
Rationale 4: Salicylates are given as anti-inflammatory agents to reduce pain and fever.
Global Rationale: Salicylates have indication for analgesia, reduction of mild to moderate inflammation, lowering body temperature, and suppression of platelet aggregation. They are typically given by the oral route, but do have side effects such as inhibiting platelet aggregation.
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