A client who has been diagnosed with Addison disease will likely experience which of the following lab results related to the absence of aldosterone?
A) Serum potassium levels elevated
B) Increased serum sodium levels
C) Elevated creatinine levels
D) Decreased serum chloride levels
Ans: A
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Aldosterone exerts a strong influence on potassium secretion in the distal and collecting tubules. In the absence of aldosterone, as occurs in Addison disease, potassium secretion is markedly decreased, causing blood levels to increase. In the presence of aldosterone, almost all the sodium in the distal tubular fluid is reabsorbed, and the urine essentially becomes sodium free. In the absence of aldosterone, virtually no sodium is reabsorbed from the distal tubule, and excessive amounts of sodium are lost in the urine.
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