Most p53 mutations that result in cancer are a result of loss of function in p53. Describe one method through which a gain-of-function mutation in p53 could cause cancer

What will be an ideal response?


The gain-of-function mutation in p53 could result in the overproduction of chromatin-remodeling enzymes. The improper expression of these enzymes would likely result in misexpression of other genes and could lead to tumorigenesis.

Biology & Microbiology

You might also like to view...

In the IP3/DAG pathway, what is the effector molecule?

a. IP3 b. DAG c. PIP2 d. phospholipase C e. calcium

Biology & Microbiology

The structure of the cartilaginous and bony fishes that detects vibrations in the water is the

a. anal fin. b. operculum. c. nostrils. d. lateral line.

Biology & Microbiology

One true characteristic of all animals is that they:a

are mobile. b. have a brain. c. are heterotrophs. d. have an organ system. e. only show sexual reproduction.

Biology & Microbiology

Four of the following can cause birth defects. Which one is the exception?

a. tobacco b. alcohol c. poor nutrition d. rubella e. folic acid

Biology & Microbiology