Bacteria that carry a nonsense mutation in an essential gene can survive if they also possess a suppressor tRNA that is capable of inserting an amino acid at the site of the premature stop codon

How are such bacterial strains capable of terminating at the normal stop codons in the rest of the polypeptides?
What will be an ideal response?


Ans: Suppression is not efficient because suppressor tRNAs must compete with release factors that cause chain termination at the stop codons in most other polypeptides.

Biology & Microbiology

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