According to genetic theory, aging is an involuntarily inherited process that operates over time to alter cellular or tissue structures. Which of the following findings support this theory? (Select all that apply.)
1. Decreased amounts of adrenocorticotropic hormone, resulting in less-efficient stress response
2. The development of collagen
3. The development of lipofuscin
4. The increased frequency in the occurrence of cancer
5. The increased frequency in the occurrence of autoimmune disorders
2, 3, 4, 5
Rationale: According to genetic theory, aging is an involuntarily inherited process that operates over time to alter cellular or tissue structures. This theory suggests that life span and longevity changes are predetermined. The development of free radicals, collagen, and lipofuscin in the aging body, and an increased frequency in the occurrence of cancer and autoimmune disorders, provide some evidence for this theory and the proposition that error or mutation occurs at the molecular and cellular level. Decreased amounts of adrenocorticotropic hormone, resulting in less-efficient stress response is part of the normal aging process of the endocrine system.
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