A man has a mutation in a mitochondrial gene encoding a subunit of the ATP synthase complex. The mutation leads to a defective ATP synthase that is not able to synthesize ATP effectively, and this in turn leads to extreme muscle weakness in the affected individual. If this man has children, what is the likelihood that they will inherit this disease from him?
A. 100%
B. 50%
C. 25%
D. 0%
E. 75%
Answer: D
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