A 1-year-old boy is evaluated for a suspected immune deficiency. He has a history since birth of eczema, recurrent rashes, and diarrhea. His white blood cell count (WBC) count is 6.75/uL (normal values: 5.0-10.8 x 103 uL) with a normal differential. Platelet count is 35,000 (normal values: 150,000- 350,000/uL), and the platelets are small. His IgG is 750 mg/dL (normal values: 600-1,500 mg/dL). IgM is 30 mg/dL (normal values; 75-150 mg/dL). IgA is 475 mg/dL (normal values: 50-125 mg/dL). IgE is 750 mg/dL (10-50 mg/dL). The boy's blood is typed as O-positive, and he does not have anti-A or anti-B antibodies. Flow cytometry performed on his blood shows 11% CD19 (normal values: 5%-20%) and 50% CD3 cells (normal values: 60%-80%) with a normal ratio of CD4:CD8. T-cell function tests are
abnormal. This boy most likely has:
A. Bruton's tyrosine kinase deficiency.
B. Wiskott-Aldrich syndrome.
C. DiGeorge anomaly.
D. ataxia telangiectasia.
Ans: B. Wiskott-Aldrich syndrome.
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An organ is defined as
a. a single tissue grouped together to perform a specific function. b. 2 or more tissues in specific proportions grouped together to perform a specific function. c. cells of different tissues linked together by the circulatory system to allow multiple functions. d. only the reproductive parts in plants. e. none of these.
Which blood type is the universal donor?
a. A only b. B only c. AB d. O e. Both AB and O
Which blood type is rare
?
a. A only b. B only c. AB d. O e. Both AB and O
One of the primary functions of RNA molecules is to _____
A) transmit genetic information to offspring B) function in the synthesis of proteins C) make a copy of itself, thus ensuring genetic continuity D) act as a pattern or blueprint to form DNA