Consider a gene in mice that is normally maternally imprinted. If a deletion occurred in the gene, rendering it nonfunctional, what would be the expected phenotypic result?
A. If the mutation occurred in the maternal copy of the gene, the mouse would be mutant, but if the mutation occurred in the paternal copy of the gene, the mouse would be wild type.
B. If the gene behaves in a dominant manner, the mouse would be mutant, but if the gene behaves in a recessive manner, the mouse would be wild type.
C. If the mutation occurred in the maternal copy of the gene, the mouse would be wild-type, but if the mutation occurred in the paternal copy of the gene, the mouse would be mutant.
D. Because the gene is maternally imprinted, all female mice would be mutant, but all male mice would be wild type.
E. Because the gene is maternally imprinted, all female mice would be wild type, but all male mice would be mutant.
Ans: C. If the mutation occurred in the maternal copy of the gene, the mouse would be wild-type, but if the mutation occurred in the paternal copy of the gene, the mouse would be mutant.
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