Which of the following categories of oral antidiabetic agents are used in patients with type 2 diabetes to inhibit the production of glucose by the liver and thus control blood glucose?
A) Sulfonylureas
B) Biguanides
C) Thiazolidinediones
D) Alpha glucosidase inhibitors
Ans: B
Feedback: Biguanides inhibit the production of glucose by the liver and are in used in type 2 diabetes to control blood glucose levels. Sulfonylureas exert their primary action by directly stimulating the pancreas to secrete insulin and therefore require a functioning pancreas to be effective. Thiazolidinediones enhance insulin action at the receptor site without increasing insulin secretion from the beta cells of the pancreas. Alpha glucosidase inhibitors work by delaying the absorption of glucose in the intestinal system, resulting in a lower postprandial blood glucose level.
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