Histone modification:
A. is fixed; once a histone is modified, it stays
that way and the genes with which it is
associated are turned on or off permanently.
B. is fixed, but this has no effect on whether
genes are expressed.
C. is randomâ€"sometimes the lysines are
modified and sometimes they're not, but the
state is independent of the environment or
cell type.
D. can change over time in response to
environmental cues, allowing genes to be
turned on or off as needed.
E. can change over time in response to
environmental cues, but this has no effect on
gene expression.
D
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