What is retinoblastoma, and what is its supposed genetic basis?

What will be an ideal response?


Retinoblastoma is cancer of the retinal cells of the eye. A familial form is known (about 40 percent of all cases), which is caused by a dominant gene. It occurs in a frequency of about 1/17,000, usually appearing at 1 to 3 years of age. A second form of retinoblastoma is not familial (60 percent of all cases), develops later in life, and usually involves only one eye. Two mutations are thought to be required for the disease to occur.

Biology & Microbiology

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Hair cells are found in structures represented by which numbers?

A) 1 and 2 B) 3 and 4 C) 5 and 7 D) 6 and 8 E) 9 and 10

Biology & Microbiology

Genetic abnormalities that occur before fertilization may result in some tissues of the body differing in their genetic composition. This is called mosaicism

Indicate whether the statement is true or false

Biology & Microbiology

Ctenophores feed on:

a. phytoplankton. b. benthic algae. c. planktonic animals. d. detritus. e. DOM.

Biology & Microbiology

Craig Mellow investigated RNA interference by injecting antisense and double-stranded RNAs into C. elegans. If the antisense and double-stranded RNAs were very similar, but not identical, to C. elegans mex-3, what would be the results of their experiment?

A. Virtually all the C. elegans mex-3 RNA would be degraded, so embryos from worms injected with antisense and double-stranded RNA would not be green. B. Many different C. elegans RNAs would be degraded, so embryos from worms injected with antisense and double-stranded RNA would most likely be dead. C. More C. elegans mex-3 mRNA would be produced by transcription, so embryos from worms injected with antisense and double-stranded RNA would be green. D. The C. elegans mex-3 RNA would be inhibited, but not degraded, so the embryos from worms injected with antisense and double-stranded RNA would be green.

Biology & Microbiology