A patient experiences severe muscle weakness, and the provider orders edrophonium bromide (Tensilon). The patient begins to show improved muscle strength within a few minutes after administration of this drug
The nurse anticipates the provider will order which drug?
a. Atropine sulfate
b. Edrophonium bromide (Tensilon)
c. Intravenous immune globulin (IVIG)
d. Pyridostigmine HCl (Mestinon)
ANS: D
In this case, edrophonium is used to diagnose myasthenia gravis. Since symptoms improved with the AChE inhibitor, the patient will benefit from a longer-acting AChE inhibitor such as pyridostigmine. Atropine is given for AChE inhibitor overdose. Edrophonium is very short-acting, so it will not be used for treatment. IVIG is used when other AChE inhibitors fail.
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