The protein SOS is a guanine nucleotide exchange factor for Ras. SOS helps facilitate the exchange of GDP for GTP. What would be the effect of a mutation that inhibits the interaction between SOS and Ras?
A. Ras would be more likely to hydrolyze GTP to GDP.
B. GDP would remain bound to Ras, thereby preventing Ras activation.
C. GTP would remain bound to Ras, thereby keeping Ras constitutively active.
D. There would be no effect.
Answer: B
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