A client with Parkinson disease is prescribed a medication that affects a particular central nervous system neurotransmitter. Which neurotransmitter is the medication acting on to treat the symptoms of Parkinson disease?
1. Acetylcholine
2. Norepinephrine
3. An endorphin
4. Gamma aminobutyric acid (GABA)
Correct Answer: 1
Rationale 1: Cholinergic synapses utilize acetylcholine as the neurotransmitter. Cholinergic synapses are especially important in the pathophysiology of Parkinson disease and Alzheimer disease.
Rationale 2: Norepinephrine can be excitatory or inhibitory, and it plays a role in depression, memory, and panic attacks.
Rationale 3: The endorphin receptor molecule is the opioid receptor, which is involved in pain reduction.
Rationale 4: GABA is the primary inhibitory neurotransmitter in the CNS, and it plays a role in anxiety disorders and seizures.
Global Rationale: Cholinergic synapses utilize acetylcholine as the neurotransmitter. Cholinergic synapses are especially important in the pathophysiology of Parkinson disease and Alzheimer disease. Norepinephrine can be excitatory or inhibitory, and it plays a role in depression, memory, and panic attacks. The endorphin receptor molecule is the opioid receptor, which is involved in pain reduction. GABA is the primary inhibitory neurotransmitter in the CNS, and it plays a role in anxiety disorders and seizures.
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