An individual with poststroke depression is receiving an SSRI. What is the rationale for giving the medication at breakfast and again at midday?
a. Prevent insomnia
b. Prevent toxic reactions
c. Decrease afternoon sleepiness
d. Give an opportunity to monitor behavior closely
ANS: A
CNS stimulants may cause insomnia if given late in the day. Toxicity is a result of excessive medication in the system, not when it is administered. The drowsiness resulting from SSRI use would not be minimized if taken as described. There is no expectation that resulting be-haviors will need to be so closely monitored.
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