During the course of obtaining a genetic history from a female client, you note that there is a family history of a genetic disease on the maternal side but no evidence of symptomatology in the client or the client's children, two girls
Which observation can you make related to genetic expression?
a. Autosomal dominant expression is observed.
b. X-linked dominant trait is observed.
c. More information is needed to determine the answer.
d. Autosomal recessive expression is observed and both the children will be carriers of the disease process.
ANS: C
Because we have no information about the father and/or paternal side, the other stated options do not apply. If an autosomal dominant expression were present in the family history, the client would be symptomatic. It is more likely to see X-linked recessive traits than X-linked dominant traits and, again, the client and children are not symptomatic. Although an autosomal recessive expression may be present, we cannot predict that the children will be carriers. There is a 25% chance of being affected.
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