Which are typically used for positional cloning of a disease gene in humans? (Select all that apply.)

A) analysis of several human pedigrees in which the disease is segregating
B) genotyping of diseased and healthy individuals at millions of anonymous polymorphisms using microarrays
C) sequencing candidate genes
D) a multigenerational selective breeding program


A) analysis of several human pedigrees in which the disease is segregating

B) genotyping of diseased and healthy individuals at millions of anonymous polymorphisms using microarrays

C) sequencing candidate genes

Biology & Microbiology

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What will be an ideal response?

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Ethanol is an inhibitor of ADH. Therefore, a person

consuming a mixed drink excretes a. less water because ADH promotes reabsorption. b. the alcohol because ADH cannot degrade it. c. ketone bodies formed from the alcohol. d. more water because ADH normally promotes reabsorption. e. more water plus the alcohol due to the ADH inhibition.

Biology & Microbiology