The nurse is providing education regarding ketoconazole (Nizoral). The nurse knows the client has understood the teaching when the client states:
1. "I could develop nausea, vomiting, and abdominal pain with this medication."
2. "I cannot take this medication longer than 10 days."
3. "I should take this medication on an empty stomach."
4. "I could develop resistance to this medication if I take it too often."
Correct Answer: 1
Rationale 1: The most common side effect of ketoconazole is nausea.
Rationale 2: The client might need to take the medication for several weeks.
Rationale 3: To prevent gastric upset, the medication should be taken with food or milk.
Rationale 4: Clients taking ketoconazole do not develop resistance.
Global Rationale: The most common adverse effects are nausea and vomiting, which can affect over 50% of patients taking high doses of the drug. To prevent gastric upset, the medication should be taken with food that does not decrease stomach acidity. Therapy may be extended over several weeks and resistance does not develop,
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