How might mutations in the APC gene that lead to mis-folded APC protein result in a change of Beta-catenin signaling levels?
a) APC is a transcription factor that binds and regulates the Beta-catenin promoter
b) Mis-folded APC will most likely result in lower levels of intact Beta-catenin in the cell
c) Mis-folded APC may prevent assembly of the protein complex that degrades Beta-catenin
d) Mis-folded APC will prevent Wnt signals from binding the frizzled receptor, and elevated Beta-catenin signaling will result
Answer: c) Mis-folded APC may prevent assembly of the protein complex that degrades Beta-catenin
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A. decrease the composition of cholesterol in the plasma membrane B. increase the composition of phospholipids with saturated fatty acid chains C. decrease the composition of phospholipids with unsaturated fatty acid chains D. decrease the length of the phospholipid fatty acyl tail. E. All of the above strategies are reasonable
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a. 1:1. b. 2:1. c. 9:3:3:1. d. 1:2:1. e. 3:1.
Which of the following is released by cells lining blood vessels and causes a decrease in blood
pressure? a. histamine b. acetylcholine c. cyclic AMP d. nitric oxide e. prostaglandin
Which would be the most unlikely location to find adhesion molecules on a newly discovered bacterium?
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