Identify which of the following statements is true regarding the transporter associated with antigen processing (TAP)
a. TAP is a homodimer composed of two identical subunits.
b. TAP transports proteasome-derived peptides from the cytosol directly to the lumen of the Golgi apparatus.
c. TAP is an ATP-dependent, membrane-bound transporter.
d. Peptides transported by TAP bind preferentially to MHC class II molecules.
e. TAP deficiency causes a type of bare lymphocytes syndrome resulting in severely depleted levels of MHC class II molecules on the surface of antigen-presenting cells.
C
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