Which drug class, with a negative inotropic effect, is prescribed for the treatment of heart failure?
1. Diuretics
2. Cardiac glycosides
3. Beta-adrenergic blockers
4. Phosphodiesterase inhibitors
3
Rationale 1:Diuretics increase urine flow and lower blood volume. They do not have inotropic effects on the heart.
Rationale 2: Cardiac glycosides have a positive inotropic effect.
Rationale 3: Beta-adrenergic blockers have a negative inotropic effect.
Rationale 4:Phosphodiesterase inhibitors have a positive inotropic effect.
Global Rationale: Beta-adrenergic blockers have a negative inotropic effect. Cardiac glycosides and phosphodiesterase inhibitors have a positive inotropic effect. Diuretics increase urine flow and lower blood volume.
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