An immune compromised patient is exposed to hepatitis A virus. The physician orders an injection of immunoglobulin as prophylaxis. What adverse effects would the nurse advise the patient might occur? (Select all that apply.)

A) Fever
B) Rhinitis
C) Angioedema
D) Severe abdominal pain
E) Urticaria


A, C, E
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Adverse effects include tenderness, muscle stiffness at site of injection; urticaria, angioedema, nausea, vomiting, chills, fever, and chest tightness. An immune compromised patient would not be told to watch for rhinitis or severe abdominal pain because these are not anticipated adverse effects.

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