How do blood-pressure-lowering diuretics function?
What will be an ideal response?
Answer: Most act to reduce Na+ reabsorption, causing more Na+ and water to be lost in the urine, increasing urine output. However, the location of function varies. Loop diuretics block Na+ reabsorption in the ascending loop by blocking the NaKCl channel. Potassium-sparing diuretics act on the cortical collecting duct, blocking aldosterone or Na+ channels on the apical membrane. Osmotic diuretics such as mannitol are filtered but not reabsorbed. As these increase osmotic pressure in the lumen, water is retained in the lumen, increasing urine output.
You might also like to view...
The sole function of an organ is to manufacture a substance secreted from or used within the body.
Answer the following statement true (T) or false (F)
What is the Latin term for "short"?
A. Minor B. Minimus C. Brevis D. Punctum
During the process of mitosis, chromatids separate during
A) prophase. B) metaphase. C) interphase. D) telophase. E) anaphase.
The lateral sulcus is superior to the
A. insula. B. temporal lobe. C. frontal lobe. D. parietal lobe. E. occipital lobe.