A nursing student asks a nurse about flucytosine [Ancobon]. Which statement by the nurse is correct?
a. "Flucytosine has a broad antifungal spec-trum."
b. "Irreversible neutropenia and thrombocy-topenia may occur with this drug."
c. "Resistance is common with this medica-tion."
d. "Severe hepatic injury is common and limits this drug's use."
C
The development of resistance during flucytosine therapy is common and is a serious clinical problem. Flucytosine has a narrow antifungal spectrum. Neutropenia and thrombocytopenia may occur but are reversible. Severe hepatic injury is rare; mild and reversible hepatic dysfunction is common.
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