Clients with chronic obstructive lung disease (COPD) may experience airway closure at the end of normal instead of low lung volumes, which result in:

A) Airway constriction of the main bronchus
B) Release of epinephrine, a catecholamine, which causes airway dilation
C) An increase in the physiological dead space in alveoli that are perfused but not ventilated
D) Trapping of large amounts of air that cannot participate in gas exchange


Ans: D
Feedback:
The pressure needed to overcome the tension in the wall of a sphere or an elastic tube is inversely related to its radius; therefore, the small airways close first, trapping some air in the alveoli. This trapping of air may be increased in older persons and persons with chronic lung disease owing to a loss in the elastic recoil properties of the lungs. In these persons, airway closure occurs at the end of normal instead of low lung volumes, trapping larger amounts of air that cannot participate in gas exchange. It does not result in airway constriction, release of catecholamines, or an increase in the physiological dead space.

Health & Biomechanics

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