Mr. Ashoor is a 29-year-old asthmatic patient who takes MDI albuterol for wheezing and typically gets quick relief following two puffs. After he mowed the lawn today, he realized he was having a rapid decrease in responsiveness to his albuterol
He tried taking it again but still had no relief. This situation is described by which of the following terms used to refer to drug responsiveness?
a. Hypersensitivity
b. Idiosyncratic effect
c. Tolerance
d. Tachyphylaxis
ANS: D
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