Which of the following statements about bone mass and the elderly is accurate?
A) Bone mass is increased with aging due to all the wear and tear of the joints.
B) Once skeletal growth has been attained, there is no longer any replacement or repair.
C) Bone resorption and formation are no longer perfectly coupled, and bone mass is lost.
D) Hormones, like PTH, are much slower to be released as one ages.
Ans: C
Feedback:
In the adult, the length of one sequence (i.e., bone resorption and formation) is approximately 4 months. Ideally, the replaced bone should equal the absorbed bone. If it does not, there is a net loss of bone. In the elderly, for example, bone resorption and formation no longer are perfectly coupled, and bone mass is lost. Once skeletal growth has attained its adult size, the breakdown and renewal of bone that is responsible for skeletal maintenance is initiated at sites that require replacement or repair. This process is called bone remodeling. As long as the parathyroid glands are healthy, they will remain as important regulators of calcium and phosphate levels in the blood.
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