The patient and her partner are carriers of sickle-cell disease. They are considering prenatal diagnosis with either amniocentesis or chorionic villus sampling (CVS)
Which statements indicate that further teaching is needed on these two diagnostic procedures? Note: Credit will be given only if all correct choices and no incorrect choices are selected. Select all that apply. 1. "Chorionic villus sampling carries a lower risk of miscarriage."
2. "Amniocentesis can be done earlier in my pregnancy than CVS."
3. "Neither test will conclusively diagnose sickle-cell disease in our baby."
4. "The diagnosis comes sooner if we have CVS, not amniocentesis."
5. "Amniocentesis is more accurate in diagnosis than the CVS."
1,2,5
Rationale 1: CVS carries twice the risk of spontaneous abortion that amniocentesis does. Both tests diagnose genetic disorders.
Rationale 2: An amniocentesis is not done until around 14 weeks' gestation, when there is enough amniotic fluid to test. A CVS is done in the first 8 weeks of pregnancy.
Rationale 3: This is a true statement.
Rationale 4: CVS is performed at 8–12 weeks' gestation, and amniocentesis is performed at 11–14 weeks.
Rationale 5: Both are equally diagnostic, but because CVS is performed earlier in pregnancy, and the results are usually back in about 24 hours, the greatest advantage to CVS is earlier diagnostic information.
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