A patient has a variety of cellular problems, including proteins in the endomembrane system going to the wrong locations, and no synthesis of estrogen or testosterone. Identify the organelle-symptom pair that is defective.
A. A problem in the rough ER is responsible for the protein location problem, and a problem in the smooth ER is responsible for the estrogen and testosterone problem.
B. A problem in the smooth ER is responsible for the protein location problem, and an issue in the Golgi apparatus is responsible for the production of estrogen and testosterone.
C. Protein sorting normally occurs in the peroxisomes and is not functioning properly, and a damaged rough ER cannot produce estrogen and testosterone.
D. The protein location problem is associated with the Golgi apparatus and the lack of testosterone production is an issue with the rough ER.
Answer: A
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