A middle-aged female has presented to the emergency department (ED) after 36 hours of severe diarrhea that shows no sign of abating. The patient's family members are asking that the care team provide medications to resolve her diarrhea
The ED nurse should be aware that the use of diphenoxylate (Lomotil) would be contraindicated in which of the following circumstances? A) The patient has a documented history of laxative abuse.
B) The patient's diarrhea is caused by the ingestion of toxins.
C) The patient's diarrhea is attributable to psychosocial stress.
D) The patient has an allergy to aspirin.
B
Feedback:
Contraindications to the use of diphenoxylate with atropine include diarrhea caused by toxic materials, microorganisms that penetrate intestinal mucosa (e.g., pathogenic E. coli, Salmonella, Shigella), and antibiotic-associated colitis. Laxative abuse, allergies to aspirin, and the presence of stress do not contraindicate the safe use of Lomotil.
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