A father and mother are carriers of phenylketonuria (PKU). Their 2-year-old daughter has PKU. The couple told the nurse that they were planning to have a second baby
Because their daughter has PKU, they believe that their next baby is sure not to be affected. Which of the following responses by the nurse is most accurate? 1. "Good planning; you need to take advantage of the odds in your favor.".
2. "I think you'd better check with your doctor first.".
3. "You are both carriers, so each baby has a 25% chance of being affected.".
4. "The ultrasound indicates a boy, and boys are not affected with PKU.".
3
1. Incorrect. There is still an increased likelihood of this couple having another child with PKU. Having already one child with PKU does not guarantee that they will not have another.
2. Incorrect. They do need to discuss their options with their doctor. However, an opportune time has presented itself for the couple to receive correct teaching regarding inherent genetic risks.
3. Correct. There is a 1 in 4 chance that each child produced by this couple will be affected with PKU disorder.
4. Incorrect. There is no correlation with gender because PKU disorder is an autosomal re-cessive pattern disorder.
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