The nursing instructor is talking with the pathophysiology class
What diffuse connective tissue disease would the instructor tell the class is the result of an autoimmune reaction that results in phagocytosis, producing enzymes within the joint that break down collagen and cause edema?
A) Rheumatoid arthritis (RA)
B) Systemic lupus erythematosus
C) Osteoporosis
D) Polymyositis
Ans: A
Feedback: In RA, the autoimmune reaction results in phagocytosis, producing enzymes within the joint that break down collagen, cause edema and proliferation of the synovial membrane, and ultimately form pannus. Pannus destroys cartilage and bone. SLE, osteoporosis, and polymyositis do not result in phagocytosis.
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