A 45-year-old man has just been diagnosed with Huntington disease. He and his wife are concerned about their four children. What will the nurse understand about the children's possibility of inheriting the gene for the disease?
A) Each child will have a 25% chance of inheriting the disease.
B) Each child will have a 50% chance of inheriting the disease.
C) Each child will have a 75% chance of inheriting the disease.
D) Each child will have no chance of inheriting the disease.
Ans: B
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Huntington disease is an autosomal dominant disorder. Autosomal dominant inherited conditions affect female and male family members equally and follow a vertical pattern of inheritance in families. A person who has an autosomal dominant inherited condition carries a gene mutation for that condition on one chromosome pair. Each of that person's offspring has a 50% chance of inheriting the gene mutation for the condition and a 50% chance of inheriting the normal version of the gene.
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