The nurse understands that microsomal enzymes are important in which pharmacokinetic factor in drug therapy?
a. absorption c. biotransformation
b. distribution d. liberation
ANS: C
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A Incorrect: Absorption does not involve microsomal enzymes.
B Incorrect: Distribution does not involve microsomal enzymes.
C Correct: Microsomal enzymes originate in the smooth endoplasmic reticulum of the liver and are necessary for metabolism/biotransformation of drugs.
D Incorrect: Liberation does not involve microsomal enzymes.
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