Describe the three immunological mechanisms responsible for the destruction of red blood cells in autoimmune hemolytic anemia
What will be an ideal response?
(i) Red blood cells coated with antibodies against red blood cell-surface components bind to splenic macrophages via Fc receptors, inducing phagocytosis of the red blood cell by receptor-mediated endocytosis. (ii) Red blood cells bound by antibodies against red blood cells fix complement, which causes deposition of C3b on the surface of the red blood cell. C3b then binds to the receptor CR1 on splenic macrophages, inducing phagocytosis of red blood cells. (iii) Antibody against red blood cells triggers the complement cascade and the formation of membrane-attack complexes on the red blood cell, leading to cell lysis.
You might also like to view...
_____ is defined as the ability to produce maximum force in the shortest time
a. Agility b. Balance c. Power d. Speed
A nephropexy is done to correct ________
A) nephrolithiasis B) nephropathy C) nephrosclerosis D) nephroptosis
Rylie is an oncology nurse who is trying to conceive a baby. Is it safe for her to administer cytotoxic chemotherapy?
A) Possibly. She may be able to administer select medications depending on the type of cytoxic drug being administered. B) Yes, as long as she does not handle them at the time she is ovulating. C) Yes, as long as she uses standard chemotherapeutical administration precautions. D) No. Women who are pregnant, breast-feeding, or actively trying to conceive a child should not care for patients receiving cytotoxic drugs.
The term used to describe a buttocks-first presentation of the fetus at delivery is ________.
Fill in the blank(s) with the appropriate word(s).