Give some reasons as to why some people become obese whereas others do not.

What will be an ideal response?


(1) differences in consumption: many factors lead some people to eat more than others who have comparable access to food
(2) differences in energy expenditure: the most obvious difference is that people differ substantially in the amount of exercise they get; differences in basal metabolic rate and in the ability to react to fat increases by diet induced thermogenesis; third factor is NEAT (non exercise activity thermogenesis), which is generated by activities such as dieting and the maintenance of posture and muscle tone
(3) differences in gut microbiome composition: the microbes in our gut can have major influences on brain and behaviour, for example, they can influence neurodevelopment, the blood-brain barrier, and even myelination of certain CNS axons
(4) genetics and epigenetic: about 100 human chromosome loci (regions) have already been linked to obesity; evidence that transgenerational epigenetic effects can predispose subsequent generations to obesity

Biology & Microbiology

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