The patient has taken epoetin alfa (Epogen) with good results for several months. On this visit, the nurse analyzes the patient's lab results and finds indications of severe anemia and cytopenias. What order will the nurse anticipate receiving?
A) Increase the dosage of Epogen.
B) Change the patient to another erythropoiesis-stimulating agent.
C) Discontinue Epogen.
D) Begin administering Epogen IV instead of subcutaneously.
C
Feedback:
In patients treated with Epogen or any drug in this class who develop severe anemia after improvement, the drug should be stopped and should not be changed to another drug in the class because it is likely due to patient's development of neutralizing antibodies. Increasing the dosage will not help and changing the route of administration will not reverse the process after antibodies have formed.
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