Considering anemia, what effect do vitamin B12 and folate deficiencies have on red blood cells?
a. They are unable to differentiate into erythrocytes.
b. They contain malformed hemoglobin molecules.
c. O2-carrying capacity is decreased.
d. Their life span is shorter.
ANS: D
These deficiencies lead to defective erythrocytes that die prematurely, which decreases their numbers in the circulation, causing anemia. These deficiencies do not cause the RBCs to lack differentiation, contain malformed hemoglobin, or experience diminished O2-carrying capacity.
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