Saturation occurs when
A. intramolecular interactions are disrupted in the enzyme, decreasing its efficiency and decreasing reaction rate.
B. the substrate is denatured and the enzyme cannot catalyze any changes in its structure.
C. enzymes become fatigued and can no longer catalyze changes in the substrate.
D. there is so much enzyme present that the reaction rate decreases if more is added.
E. all enzymes are busy and further increases in substrate concentration will not increase reaction rate.
Answer: E
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