Protein and blood cell leakage into the filtrate that occurs in many forms of glomerular disease is a result of changes in the structure and function of the glomerular:
A) Renal corpuscle
B) Bowman capsule
C) Peritubular network
D) Basement membrane
Ans: D
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The basement membrane is a meshwork of collagen fibers, with slit pores between the fibers creating size-dependent permeability that (normally) does not allow large molecules, such as protein and blood cells through. The renal corpuscle contains the Bowman capsule and capillaries surrounding it. Peritubular capillary network is a low-pressure reabsorptive system that permits rapid fluid/solute transfer to/from the tubules.
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