For each of the descriptions in questions 11-13, select the tumor immunotherapy strategy (A-J) that is best match

A. Killed tumor vaccine
B. DNA vaccines
C. Interleukin (IL)-2
D. IL-4
E. GM-CSF (granulocyte-macrophage colony-stimulating factor)
F. Anti-CD3 antibodies
G. Lymphokine-activated killer cells
H. Anti-Her2/neu antibodies
I. Anti-idiotypic antibodies
J. Dendritic cell vaccine

Component of adoptive cellular immunotherapy used with IL-2 and/or chemotherapeutic drugs


ANS: G. Lymphokine activated killer (LAK) cells are activated natural killer cells derived from peripheral blood leukocytes of tumor patients by in vitro high-dose interleukin (IL)-2 treatment. LAK cells have been used in adoptive cellular immunotherapy protocols for certain cancers, such as melanoma and renal cell carcinoma, usually in conjunction with IL-2 and/or chemotherapeutic drugs.

Health & Biomechanics

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