Drugs that have a significant first-pass effect:
1. Must be given by the enteral (oral) route only
2. Bypass the hepatic circulation
3. Are rapidly metabolized by the liver and may have little if any desired action
4. Are converted by the liver to more active and fat-soluble forms
3
You might also like to view...
The nurse is caring for a 2-year-old girl who is wheezing and has difficulty breathing. Which action would provide the most useful information?
A) Inquiring about child safety in the home B) Asking about the birth status of the child C) Discussing the child's diet with the parents D) Asking the parents if they smoke in the home
An older patient is experiencing overflow incontinence. What should the nurse identify as causes for this change in urinary functioning? Standard Text: Select all that apply
1. History of dementia 2. Enlarged prostate gland 3. Treatment for gastric ulcers 4. Diagnosis of diabetes mellitus 5. Prescribed a calcium channel blocker
Performance attributes of an individual are determined by ability and ____
a. Aptitude b. Knowledge c. Motivation d. Skill
When providing discharge instructions to a patient who has been prescribed home oxygen therapy, a nurse teaches the patient to do which of the following? Select all that apply
1. Burn candles near the oxygen source. 2. Avoid smoking near the oxygen source. 3. Avoid wearing wool blankets or sweaters. 4. Use extension tubing to move around the house. 5. Use an open-flame heater near the oxygen source.