The nurse is teaching a group of student nurses the role of naloxone in treating opioid toxicity. How should the nurse explain the mechanism of action?
1. Naloxone blocks the pain transmission sites.
2. Naloxone competes with the opioid at the receptor sites.
3. Naloxone binds with the opioid to prevent the action of the opioid.
4. Naloxone blocks the pain perception of the client.
Correct Answer: 2
Rationale 1: Naloxone does not work in the transmission of pain.
Rationale 2: Naloxone competes with the opioid at the mu and kappa receptor sites.
Rationale 3: Naloxone does not bind with the opioid.
Rationale 4: Naloxone does not block the pain perception of the client.
Global Rationale: Naloxone competes with the opioid at the mu and kappa receptor sites. Naloxone does not work in the transmission of pain, does not bind with the opioid, and does not block the pain perception of the client.
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