The nurse is preparing to administer methotrexate by mouth to a client with cancer. For what reasons would the nurse use the PO route rather than the other routes of administration?
Standard Text: Select all that apply.
1. The PO route is more acceptable to the client.
2. The PO route decreases the risk for phlebitis.
3. The PO route decreases the risk for tissue necrosis.
4. The PO route decreases the risk for nausea.
5. The PO route decreases the risk for vomiting.
Correct Answer: 1,2,3
Rationale 1: The PO route is more acceptable to clients than the other routes of administration.
Rationale 2: Receiving chemotherapeutic agents by mouth rather than intravenously decreases the risk for phlebitis.
Rationale 3: Receiving chemotherapeutic agents by mouth rather than intravenously decreases the risk for tissue necrosis.
Rationale 4: Receiving chemotherapeutic agents by mouth does not decrease the risk for nausea.
Rationale 5: Receiving chemotherapeutic agents by mouth does not decrease the risk for vomiting.
Global Rationale: The PO route is the easiest, most convenient, and least expensive route for chemotherapy administration. Patients can self-administer their PO chemotherapy medications at home. This route decreases risk of phlebitis and tissue necrosis, but does not decrease adverse effects such as nausea and vomiting.
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