A patient with Von Willebrand disease (vWD) has experienced recent changes in bowel function that suggest the need for a screening colonoscopy. What intervention should be performed in anticipation of this procedure?
A) The patient should not undergo the normal bowel cleansing protocol prior to the procedure.
B) The patient should receive a unit of fresh-frozen plasma 48 hours before the procedure.
C) The patient should be admitted to the surgical unit on the day before the procedure.
D) The patient should be given necessary clotting factors before the procedure.
Ans: D
Feedback:
A goal of treating vWD is to replace the deficient protein (e.g., vWF or factor VIII) prior to an invasive procedure to prevent subsequent bleeding. Bowel cleansing is not contraindicated and FFP does not reduce the patient's risk of bleeding. There may or may not be a need for preprocedure hospital admission.
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